The three most recent major releases of macOS are supported. There are several methods and deployment tools that you can use to install and configure Defender for Endpoint on Mac. Administrative privileges on the device (in case of manual deployment).
How to install Microsoft Defender for Endpoint on Mac Prerequisites
To get the latest features, including preview capabilities (such as endpoint detection and response for your Mac devices), configure your macOS device running Microsoft Defender for Endpoint to be an 'Insider' device. If you have any feedback that you would like to share, submit it by opening Microsoft Defender for Endpoint on Mac on your device and navigating to Help > Send feedback.
